Biblioteca de Fontes Oficiais

Lista completa de referências, ensaios clínicos e meta-análises que fundamentam o desenvolvimento da Blue Functional Science™.

Fontes sobre Vitamina D e TEA

The effect of vitamin D supplementation in treatment of children with autism spectrum disorder: a systematic review and meta-analysis of randomized controlled trials

Song L, et al. Nutritional Neuroscience. 2022.

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Effects of Vitamin D Supplementation on Children with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis

Choi JW, et al. Clinical Psychopharmacology and Neuroscience / PMC. 2023.

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The Association between Vitamin D Status and Autism Spectrum Disorder: A Systematic Review and Meta-Analysis

Zhou Z, et al. Nutrients. 2021.

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Vitamin D Supplementation is Beneficial for Children with Autism Spectrum Disorder: a Meta-analysis

Mazahery H, et al. Clinical Psychopharmacology and Neuroscience. 2020.

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Effect of vitamin D supplementation on inflammatory status and clinical symptoms in children with autism spectrum disorder

Eshraghi AA, et al. BMC Pediatrics. 2025.

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Fontes sobre Zinco (Zn) e TEA

Association between zinc status and autism spectrum disorder in children and adolescents: a systematic review and meta-analysis

Wu M, et al. Frontiers in Nutrition / PMC. 2025.

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Zinc Status and Autism Spectrum Disorder in Children and Adolescents: A Systematic Review

Coto-Vílchez C, et al. Nutrients. 2023.

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Nutritional Status of Children Diagnosed With Autism Spectrum Disorder: A Scoping Review

Al-Bataineh E, et al. Journal of Human Nutrition and Dietetics. 2025.

Fontes sobre Vitamina B6 (com Magnésio) e TEA

Combined vitamin B6-magnesium treatment in autism spectrum disorder

Nye C, et al. Cochrane Database / PubMed. 2005.

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Effects of High Dose of Vitamin B6 With Magnesium in Children With Autism Spectrum Disorder

Javadfar Z, et al. ClinicalTrials.gov. 2020.

Vitamin B6 and Magnesium on Neurobehavioral Status of Autism Spectrum Disorder

Damanik R, et al. ResearchGate. 2021.

Vitamin B6 and Magnesium in Autism Spectrum Disorders: Potential Mechanisms

Frustaci A, et al. CMJ Publishers. 2025.

Fontes sobre Vitamina B9 (Ácido Fólico/Folato)

Prenatal Folic Acid Supplements and Offspring’s Autism Spectrum Disorder: A Meta-analysis

Zhong C, et al. Journal of Autism and Developmental Disorders. 2022.

The association between maternal prenatal folic acid and multivitamin supplementation and ASD

Levine SZ, et al. PLOS ONE. 2018.

Folic Acid and Autism: A Systematic Review of the Current State of Knowledge

Iglesias-Vázquez L, et al. Cells. 2021.

Examining associations of folic acid supplements with ASD in offspring: A meta-analysis

Guo B, et al. Frontiers in Public Health. 2024.

The Effect of Maternal Folic Acid Supplementation on Offspring’s ASD

Zhong C, et al. Nutrients. 2025.

Fontes sobre Vitamina B12 (Metilcobalamina)

The Effectiveness of Cobalamin (B12) Treatment for Autism Spectrum Disorder: A Systematic Review

Zhang MF, et al. Journal of Personalized Medicine. 2021.

Randomized, Placebo-Controlled Trial of Methyl B12 for Children with Autism

Hendren RL, et al. Journal of Child and Adolescent Psychopharmacology. 2016.

Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in ASD

James SJ, et al. American Journal of Clinical Nutrition. 2009.

Fontes sobre Vitamina C e TEA

Scurvy as an Alarm Bell of Autistic Spectrum Disorder in the First World

Pizzo F, et al. Children. 2021.

Vitamin C combined with multiple micronutrient deficiencies in children with ASD

Xu Y, et al. Frontiers in Nutrition. 2022.

Scurvy in autism spectrum disorder-associated food selectivity: A case report

Wu S, et al. Revista Mineira de Medicina Geral. 2025.

Micronutrient deficiencies and autism spectrum disorder

CPSP. Canadian Paediatric Surveillance Program. 2025.

Fontes sobre Vitamina E e TEA

Autism Spectrum Disorder and Dietary Intake of Vitamin E: A Systematic Review

Lee S, et al. PMC. 2025.

Breaking the cycle of oxidative stress for better behavioral health in ASD

Ghozy S, et al. Asian Journal of Psychiatry. 2025.

Effect of Increasing Total Antioxidant Capacity in Autism Spectrum Disorder

Tran T, et al. ClinicalTrials.gov. 2025.

Oxidative Stress in Autism Spectrum Disorder—Current Progress

Bjørklund G, et al. Frontiers in Psychiatry. 2022.

Natural Antioxidants: A Novel Therapeutic Approach to Autism Spectrum Disorders?

Meguid NA, et al. Antioxidants. 2020.

Fontes sobre Vitamina B1 (Tiamina)

Treatment of autism spectrum children with thiamine tetrahydrofurfuryl disulfide

Lonsdale D, et al. Neuro Endocrinology Letters. 2002.

Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency

Marrs T, et al. Frontiers in Psychiatry. 2019.

The Rationale for Vitamin, Mineral, and Cofactor Treatment in Precision Medical Care

Tippens M, et al. Journal of Personalized Medicine. 2023.

Plasma vitamin levels and pathway analysis in boys with autism spectrum disorder

Wang X, et al. Scientific Reports. 2024.

Relationship between Vitamin Deficiencies and Co-Occurring Symptoms in ASD

Meguid NA, et al. Medicina. 2020.

Fontes sobre Suco de Maçã com Mirtilo e Lúpulo

Attenuation of Autism-like Behaviors by Portuguese Blueberries via Microbiota-Gut-Brain Axis

Santos M, et al. Int. J. of Mol. Sciences / MDPI / ResearchGate. 2022.

An Anthocyanin-Rich Extract Obtained from Blueberries Modulates Microbiota-Gut-Brain Axis

Santos M, et al. PMC. 2020.

The effects of wild blueberry on the cognition and mood of children

Barfoot KL. University of Reading. 2019.

Effects of a hops (Humulus lupulus L.) dry extract on depression, anxiety and stress

Kyriakidou Y, et al. Hormones / NHRI. 2017.

Mature Hop Bitter Acids Improve Cognition and Mood in Healthy Older Adults

Fukuda T, et al. HerbalGram / J. Alzheimer’s Disease. 2020.

Exploring the sedative properties of natural molecules from hop cones

Benkherouf AY, et al. Frontiers in Chemistry. 2024.

Fontes Gerais sobre Suplementação e TEA

Vitamin Interventions in ASD and ADHD: Systematic Review

Hu Y, et al. PMC. 2025.

Complementary and Alternative Medicine for Autism – A Systematic Review

Höfer J, et al. PMC. 2024.

Nutritional Supplements in Autism Spectrum Disorder: A Scoping Systematic Review

Ranjan S, et al. Indian Journal of Nutrition and Psychology. 2024.

The effect of dietary supplements on clinical aspects of ASD

Mazahery H, et al. Brain and Development. 2017.

Nutritional and Dietary Interventions for Autism Spectrum Disorder: A Systematic Review

Brondino N, et al. Pediatrics. 2017.